On the subject what we all may look like in 20 years, Minou Clark, CEO of US healthcare marketplace Realself, told Vogue Business’s beauty editor Nateisha Scott, “the risk is that the 1% could look like Benjamin Button, and the rest of us shriveled raisins.” The future of appearance is the subject of today’s Run-Through podcast. Despite the overwhelming evidence that as a culture we only grow more averse to the natural signs of aging, Scott and my fellow guest, Vogue Business America’s Editor Hilary Milnes, find reasons to be optimistic. We spoke about the novel ways we’ll prevent muscle loss, treat scars, fix our teeth, and, yes, erase those wrinkles—and how we can opt out of all of it, if we care to. Please give it a listen.